Thursday, 20 February 2014

DEPM's Professor Henry Krum profiled in The Lancet

Professor Henry Krum, head of the DEPM’s Clinical Pharmacology Unit and Director of Monash Centre of Cardiovascular Research and Education in Therapeutics has been featured by Geoff Watts, Science Journalist, in the latest issue of The Lancet.

Watts says that “If there’s one man who can be said to have put Australia on the map with respect to clinical trials in cardiovascular disease, particularly in heart failure, it’s Henry Krum…”.

Glasgow University Professor of Cardiology John McMurray said of Professor Krum, “An unusual strength is the breadth and depth of his knowledge and research spanning cardiovascular disease, diabetes, and chronic kidney disease among others.”

Professor Krum’s final 3 year data from the landmark Symplicity HTN-1 study was recently published in the Lancet. Symplicity HTN-1 was the first proof of principle demonstration of the beneficial blood pressure-lowering effect of a new technique called percutaneous renal sympathetic denervation, a minimally invasive approach to damage the nerves that surround the main artery to the kidneys which provide signals to the kidneys (and brain) to drive blood pressure up.

Talking of the history of sympathectomy Prof Krum pointed out that this isn’t a particularly new idea: “Surgically it goes back to the era before there were any of the modern pharmacological agents. It was highly effective at lowering blood pressure, but it had a lot of side-effects such as postural hypotension” he told Watts.

1 comment:

  1. Kathleen Whelan OAM17 December 2015 at 14:44

    We had the pleasure of knowing Henry for ten years - prior to his illness - whilst Peter was a DCM patient of Henry's at the Alfred Hospital Heart Centre in Melbourne, Australia.
    During those years we always found Henry to be a most caring physician, and such a humble expert in his field.
    When first diagnosed Peter's EF was 26%, and with Henry's care and prescribed Peter's DCM condition improved greatly, however, with the addition of herbal & vitamin/mineral supplements, especially selenium, Peter was able to bring his EF up to 58%, with the resulting BNP readings of 6.3, and 10.8, absolutely astounding Henry to the poiny that he said : "Peter, you technically no longer have DCM, but as you have an 83 year old heart, keep taking my medicine, but also keep doing what you are doing!"
    A Research Scientist at the Baker IDI in Melbourne was researching oxidative stress, and was undertaking trials with selenium on lab rats. We told her of Peter's experience, as CM is called "white muscle disease" in cattle and sheep, and is treated by farmers with the addition of selenium!
    Henry was also most generous with his time, and when Peter and I were on the Executive of the Cardiomyopathy Association of Australia, he was able to arrange a "free display site" for our Association at the World Cardiomyopathy Symposium being held in Melbourne that year, in the mid-late 2000s.
    As such a caring physician, and such an expert in his field, we will miss him greatly, and extend our sincere sympathy to his family, and all his colleagues around the world.
    May His Dear Soul Rest in Peace.
    Peter Lee & Kathy Whelan, South Gippsland, Australia



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