Thursday, 17 April 2014

Study finds that a drug used to treat diabetes may be causing heart failure

DEPM's Dr Ingird Hopper was recently awarded  the Cardiac Society of Australia and New Zealand (CSANZ) Travelling Fellowship to attend the American College of Cardiology Scientific Sessions in Washington, DC. She presented a meta-analysis of 50 studies of Dipeptidyl peptidase-4 inhibitors (a drug used to lower blood sugar in diabetes) and cardiovascular outcomes, demonstrating an increase in heart failure with use of this drug.

Entitled, Heart failure and Dipeptidyl peptidase-4 inhibitors, the study suggests that the use of the drug Dipeptidyl peptidase-4 inhibitors may be detrimental to patients rather than helpful. Two large-scale, placebo-controlled outcome trials are due to report in the next few years, which should provide important data to support or refute the above hypothesis. In the meantime, the study has suggested that there should be careful monitoring of patients who are taking the drug used to treat diabetes.

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