Friday, 23 January 2015

Parental exposure to solvents could increase risk of childhood brain tumours

A study co-authored by 7 researchers has found a link between childhood brain tumours and the parents’ exposure to solvents due to occupation.

Childhood brain tumours result from rapid, abnormal cell growth originating in the brain. The association between solvent exposure and CBTs have been previously researched, however due to inconsistent or irregular findings; few conclusions have been made in addressing the possible correlation.

This study aimed to determine whether parental occupational exposure with solvents could lead to an increased risk of childhood brain tumours amongst the children.

The study used a case-control model with 306 cases and 950 controls of parents with full occupational histories being utilised. Parental exposure to chlorinated solvents, benzene and aromatics were measured by date of exposure and date of birth of the child. The use of Odds Ratio and Confidence Intervals provided supporting data. The results from this study indicated that maternal exposure to chlorinated solvents before the child was born led to an increased risk of development of a brain tumour. Furthermore, paternal exposure of solvents dating back to year before conception attributed to increased risk of a tumour.

The researchers definitively conclude that parental exposure to any solvents before conception and birth indicates a positive association with childhood brain tumours.

Read the full paper here.

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