Monday, 23 February 2015

The relationship between sedentary behaviour and postmenopausal breast cancer risk factors

Dr David Dunstan from SPHPM has co-authored a paper with three other researchers from Deakin University, The Baker Institute, University of Melbourne, University of Western Australia and University of Queensland to identify relationships between sedentary behaviour changes and presumed postmenopausal breast cancer risk markers over five years.

Sedentary behavioural activities such as continuous viewing of television have been previously linked to risk of developing diabetes and a decline in cardiovascular health and possible mortality. This behaviour can also be associated with increasing risk of postmenopausal breast cancer due to inflammation and central adiposity.

A previous study revealed that there was a relationship between an individual’s body mass index, homeostatic insulin resistance and monitored sedentary activities. The study specifically explored the correlation between breast cancer risk biomarkers and inactive (sedentary) behaviour.

The study used a sample of 1,001 postmenopausal Australian women through a previous Australian Diabetes, Obesity and Lifestyle study. A multivariate linear regression was utilised to understand the relationship between biomarkers of breast cancer risk and a shift in television viewing time (identified as a sedentary activity). The biomarkers utilised included; metabolic dysfunction, adiposity and insulin resistance.

Results from the study illuminated that changes in television watching time (in hourly brackets) were positively linked with body mass index as well as circumference of the waist. It can be concluded that consistent sedentary behavioural activities such as television viewing over a long term period could lead to increased risk of breast cancer for postmenopausal females. However, it is also recommended that further research into the relationship could be beneficial to address the current lack of studies within the area.

The study is available here.

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