Friday, 3 July 2015

Professor Helena Teede featured in Endocrine Today

SPHPM's Professor Helena Teede has been featured in Endocrine Today, discussing the benefits of lifestyle changes in improving symptoms of PCOS (Polycystic Ovary Syndrome).

Professor Teede along with other researchers conducted a systematic review and meta-analysis of existing studies which critiqued lifestyle changes and metformin usage. The data was collected from nine different studies, with 608 participants suffering from PCOS.

The studies sought to compare and contrast the benefits of both metformin and lifestyle changes; just metformin; and the use of lifestyle changes and a placebo. The review identified that women who not only made lifestyle changes but also incorporated metformin into their regime reported increased weight loss, a reduced BMI and better menstruation than women who were given a placebo and different assigned lifestyle modifications.


Professor Teede said that lifestyle intervention is currently first-line treatment for women with PCOS in both prevention of weight gain and in weight loss.

"Women with PCOS are known to have higher rates of weight, greater rates of obesity and to have significant adverse health impacts from excess weight," Professor Teede said.

Research exploring the use metformin and the rising literature surrounding the benefits of metformin indicate that this modification to existing lifestyle alterations in treating and managing PCOS needs to be further explored and addressed.

"Large-scale, well-designed studies need to explore the benefits and potential adverse effects of metformin in addition to lifestyle in the longer term in both lean and overweight women and across a broader range of clinical endpoints," Professor Teede said.

You can read the article here.

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